Head of St. Clara Forschung AG

Prof. Dr med. Markus Zuber

Prof. Dr med.

Professional career

Curriculum vitae

Since 2023

Head of St. ClaraForschung AG

2020 -

Coordinator of clinical studies at the Clarunis network clinics

Since 2014

Expert Specialised body IVHSM

2000 - 2019

Chief Physician, Clinic for Visceral, Vascular and Thoracic Surgery, Olten Cantonal Hospital

2019 - 2020

Chief Physician a.i., Clinic for Visceral, Vascular and Thoracic Surgery, Bürgerspital Solothurn

2015 - 2019

Medical Director of Solothurner Spitäler AG

Memberships and commitments

List of memberships

International Society of Surgery / Société Internationale de Chirurgie

Alumni Association of the Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA

FMH for surgery

Swiss Society for Surgery

European Society of Surgical Oncology

German Society for Surgery

Pu­bli­ca­ti­ons

  • Rueff J, Weixler B, Viehl TC, Ochsner A, Warschkow R, Gueller U, Mingrone W, Zuber M. Improved qualitity of colon cancer surveillance after implementation of a personalised surveillance schedule. J Surg Oncol 2020: published ahead of print, doi: 10.1002/jso.25973
  • Marti WR, Curti G, Wehrli H, Grieder F, Graf M, Gloor M, Zuber M, Demartines N, Fasolini F, Lerf B, Kettelhack C, Andrieu C, Bigler M, Hayoz S, Ribi K, Hamel C; Swiss Group for Clinical Cancer Research (SAKK), Section Surgery. Clinical outcome after rectal replacement with side-to-end, colon-j-pouch, or straight colorectal anastomosis following total mesorectal excision: a Swiss prospective, randomized, multicentre trial (SAKK 40/04). Ann Surg. 2019 May; 269(5):827-835
  • Ribi K, Marti WR, Bernhard J, Grieder F, Graf M, Gloor B, Curti G, Zuber M, Demartines N, Andrieu C, Bigler M, Hayoz S, Wehrli H, Kettelhack C, Lerf B, Fasolini F, Hamel C; Swiss Group for Clinical Cancer Research (SAKK), Section Surgery. Quality of life after total mesorectal excision and rectal replacement: comparing side-to-end, colon-j-pouch, and straight colorectal reconstruction in a randomized, phase III trial (SAKK 40/04). Ann Surg Oncol. 2019 Oct; 26(11):3568-3576
  • Jakob MO, Guller U, Ochsner A, Oertli D, Zuber M, Viehl CT. Lymph node ratio is inferior to pN-stage in predicting outcome in colon cancer patients with high numbers of analysed lymph nodes. BMC Surg. 2018 Oct 3; 18(1): 81(1-7)
  • Hayoz C, Hermann T, Raptis DA, Brönnimann A, Peterli R, Zuber M. Comparison of metabolic outcome in patients undergoing laparoscopic Roux-en-Y gastric bypass versus sleeve gastrectomy - a systematic review and meta-analysis of randomised controlled trials. Swiss Med Wkly. 2018 Jul 5; 148: doi 10.4414/smw.2018.14633
  • Weixler B, Viehl CT, Warschkow R, Guller U, Ramser M, Sauter G, Zuber M. Comparative analysis of tumour cell dissemination to the sentinel lymph nodes and to the bone marrow in patients with non-metastasised colon cancer. A prospective multicentre study. JAMA Surg. 2017 Oct 1;152(10):912-920
  • Viehl CT, Weixler B, Güller U, Dell-Kuster S, Rosenthal R, Ramser M, Banz V, Langer I, Terracciano L, Sauter G, Oertli D, Zuber M. Presence of bone marrow micrometastases in stage I-III colon cancer patients is associated with worse disease-free and overall survival. Cancer Med. 2017 May;6(5):918-927
  • Weixler B, Rickenbacher A, Raptis DA, Viehl CT, Guller U, Rueff J, Zettl A, Zuber M. Sentinel lymph node mapping with isosulfan blue or indocyanine green in colon cancer shows comparable results and identifies patients with decreased survival: A prospective comparative single-centre trial. World J Surg. 2017 Sep;41(9):2378-2386
  • Haueter R, Schütz T, Raptis DA, Clavien PA, Zuber M. Meta-analysis of single port versus conventional laparoscopic cholecystectomy comparing body image and cosmesis. Br J Surg 2017; 104(9):1141-1159
  • Jeger V, Pop R, Forudastan F, Barras JP, Zuber M, Piso RJ. Is there a role for procalcitonin in diffenrentiating uncomplicated and complicated diverticulitis in order to reduce antibiotic therapy? A prospective diagnostic cohort study. Swiss Med Wkly 2017 Nov 29; 147: w14555. doi: 10.4414/smw.2017.14555
  • Weixler B, Warschkow R, Güller U, Zettl A, von Holzen U, Schmied BM, Zuber M. Isolated tumour cells in stage I & II colon cancer patients are associated with significantly worse disease-free and overall survival. BMC Cancer 2016; 16: 106-113
  • GlobalSurg Collaborative. Mortality of emergency abdominal surgery in high-, middle- and low-income countries. Br J Surg 2016; 103(8):971-988
  • Amicarella F, Muraro MG, Hirt C, Cremonesi E, Padovan E, Mele V, Governa V, Han J, Huber X, Droeser RA, Zuber M, Adamina M, Bolli M, Rosso R, Lugli A, Zlobec I, Terracciano L, Tornillo L, Zajac P, Eppenberger-Castori S, Trapani F, Oertli D, Iezzi G. Dual role of tumour-infiltrating T helper 17 cells in human colorectal cancer. Gut 2015; 66(4): 692-704
  • Weixler B, Warschkow R, Zettl A, Riehle HM, Guller U, Viehl CT, Zuber M. Intranodal mapping using carbon dye results in more accurate lymph node staging in colon cancer patients. World J Surg 2015; 39: 2583-2389
  • Croner RS, Geppert C-I, Bader FG, Nitsche U, Späth C, Rosenberg R, Zettl A, Matias-Guiu X, Tarragona J, Güller U, Stürzl M, Zuber M. Molecular staging of lymph node-negative colon carcinomas by One-Step Nucleic Acid Amplification (OSNA) results in an upstaging of a quarter of patients in a prospective, European, multicentre study. Br J Cancer 2014; 110: 2544-2550
  • Langer I, Guller U, Worni M, Berclaz G, Singer G, Schaer G, Fehr MK, Hess T, Viehl, CT, Bronz L, Schnarwyler B, Wight E, Infanger E, Burger D, Koechli OR, Zuber M for the Swiss Sentinel Lymph Node Study Group in Breast Cancer. Bone marrow micrometastases do not impact disease-free and obverall survival in early stage sentinel nymph node-negative breast cancer patients. Ann Surg Oncol 2014; 21: 401-407
  • Droeser RA, Dell-Kuster S, Kurmann A, Rosenthal R, Zuber M, Metzger J, Oertli D, Hamel CT, Frey DM. Long-term follow-up of a randomised controlled trial of Lichtenstein's operation versus mesh plug repair for inguinal hernia. Ann Surg 2014: 259: 966-972
  • Larusson HJ, von Holzen U, Viehl CT, Rezaeian F, Riehle HM, Oertli D, Guller U, Zuber M. Blue dye injection does not induce dissemination of epithelial cells during SLN procedure in colon cancer patients. Int J Colorectal Dis 2014; 29: 689-692
  • Nebiker CA, Han J, Eppenberger-Castori S, Iezzi G, Hirt C, Amicarella F, Cremonesi E, Huber X, Padovan E, Angrisani B, Droeser RA, Rosso R, Bolli M, Oertli D, von Holzen U, Adamina M Muraro MG, Mengus C, Zajac P, Sconoccha G, Zuber M, Tornillo L, Terracciano L, Spagnoli GC. GM-CSF production by tumour cells is associated with improved survival in colorectal cancer. Clin Cancer Res 2014; 15: 3094-3106
  • Meiers P, Cil T, Guller U, Zuber M. Sentinel lymph node biopsy in early-stage breast cancer patients: improved survival through better staging? Langenbecks Arch Surg 2013; 398:687-690
  • Droeser RA, Hirt C, Eppenberger-Castori S, Zlobec I, Viehl CT, Frey DM, Nebiker CA, Rosso R, Zuber M, Amicarella F, Iezzi G, Sconocchia G, Heberer M, Lugli A, Tornillo L, Oertli D, Terracciano L, Spagnoli G. High myeloperoxidase positive cell infiltration in colorectal cancer is an independent favourable prognostic factor. PLoS One 2013. epub adhead of print. DOI 10.1371/journal.pone.0064814. Print 2013
  • Viehl CT, Guller U, Langer I, Laffer U, Oertli D, Zuber M. Factors influencing the success of in vivo sentinel lymph node procedure in colon cancer patients: Swiss prospective, multicentre study sentinel lymph node procedure in colon cancer. World J Surg 2013; 37: 873-877
  • Droeser RA, Hirt C, Viehl CT, Frey DM, Nebiker C, Huber X, Zlobec I, Eppenberger-Castori S, Tzankov A, Rosso R, Zuber M, Muraro MG, Amicarella F, Cremonesi E, Heberer M, Iezzi G, Lugli A, Terracciano L, Sconocchia G, Oertli D, Spagnoli GC, Tornillo L. Clinical impact of programmed cell death ligand 1 expression in colorectal cancer. Eur J Cancer 2013; 49: 2233-2242
  • Wanebo HJ, LeGolvan M, Paty PB, Saha S, Zuber M, D'Angelica MI, Kemeny NE. Meeting the biological challenge of colorectal metastases. Clin Exp Metastasis 2012: 29: 821-839
  • Guller U, Zettl A, Langer I, Cabalzar-Wondberg D, Rezaeian F, Viehl CT, Demartines N, Zuber M. Molecular investigation of lymph nodes in colon cancer patients: a new road to better staging? Cancer 2012; 118: 6039-6045
  • Viehl CT, Guller U, Cecini R, Langer I, Ochsner A, Terracciano L, Riehle HM, Laffer U, Oertli D, Zuber M. Sentinel lymph node procedure leads to upstaging of patients with resectable colon cancer. Results of the Swiss prospective, multicentre study sentinel lymph node procedure in colon cancer. Ann Surg Oncol 2012; 19: 1959-1965
  • Strauss and Torney M, Rezaeian F, Loher S, Brosi P, Guller U, Terracciano L, Zuber M. Tissue banking in a regional hospital: a promising future concept? First report on fresh frozen tissue banking in a hospital without an integrated institute of pathology. World J Surg 2012; 36: 2300-2304
  • Von Holzen U, Gehrz A, Meier L, Zuber M. The AQC database represents a useful tool for quality control and scientific analysis of acute appendicitis. Swiss Med Wkly 2012; 142. doi: 10.4414/smw.2012.13617
  • Sonocchia G, Zlobec I, Lugli A, Calabrese D, Iezzi G, Karamitopoulou E, Patsouris ES, Peros G, Horcic M, Tornillo L, Zuber M, Droeser R, Muraro MG, Mengus C, Oertli D, Ferrone S, Terracciano L, Spagnoli G. Tumour infiltration by FcyRIII (CD16)+ myeloid cells is associated with improved survival in patients with colorectal carcinoma. Int J Cancer 2011; 128: 2663 - 2672
  • Viehl CT, Langer I, Guller U, Zanetti-Dällenbach R, Moch H, Wight E, Oertli D, Zuber M.Prognostic impact and therapeutic implications of sentinel lymph node micro-metastases in early-stage breast cancer patients. J Surg Oncol 2011, 103: 531-533
  • Leong SPL, Zuber M, Ferris RL, Kitigawa Y, Cabanas, R, Levenback C, Faries M, Saha S. Impact of nodal status and tumour burden in sentinel lymph nodes on the clinical outcome of cancer patients. J Surg Oncol 2011; 103: 518-530
  • Viehl CT, Ochsner A, von Holzen U, Cecini R, Langer I, Guller U, Laffer U, Oertli D, Zuber M. Inadequate quality of surveillance after curative surgery for colon cancer. Ann Surg Oncol 2010; 17: 2663-2669
  • Langer I, Guller U, Viehl CT, Moch H, Wight E, Harder F, Oertli D, Zuber M. Axillary lymph node dissection for sentinel lymph node micrometastases may be safely omitted in early-stage breast cancer patients: long-term outcomes of a prospective study. Ann Surg Oncol 2009; 16: 3366-3374
  • Langer I, Guller U, Hsu Schmitz SF, Ladewig A, Viehl CT, Moch H, Wight E, Harder F, Oertli D, Zuber M. Performing sentinel lymph node biopsy is associated with improved survival compared with level I & II axillary dissection in node negative breast cancer patients. Eur J Surg Oncol 2009; 35: 805-813
  • Langer I, Guller U, Berclaz G, Koechli OR, Moch H, Schaer G, Fehr M, Hess T, Oertli D, Bronz L, Schnarwyler B, Wight E, Uehlinger U, Infanger E, Burger D, Zuber M. Accuracy of frozen section of sentinel lymph nodes: a prospective analysis of 659 breast cancer patients of the Swiss multicentre study. Breast Cancer Res Treat 2009; 113: 129-136
  • Güller U, Kempski O, Zuber M. The bumpy path to successful academic surgery: a roadmap for the surgical resident. Eur Surg Res 2009; 43: 253-255
  • Rosenthal R, Viehl CT, Guller U, Weber WP, Adamina M, Spagnoli GC, Heberer M, Zuber M. Active specific immunotherapy phase III trials for malignant melanoma: systematic analysis and critical appraisal. J Am Coll Surg 2008; 207: 95-105
  • Adamina M, Weber WP, Rosenthal R, Schumacher R, Zajac P, Guller U, Frey DM, Oertli D, Zuber M, Heberer M, Spagnoli GC. Heterologous prime-boost immunotherapy of melanoma patients with influenza virosomes, and recombinant vaccinia virus encoding 5 melanoma epitopes and 3 co-stimularoy molecules. A multicentre phase I/II open labelled clinical trial. Surgery 2008; 29: 165-181
  • Lehmann K, Guller U, Bugnon S, Zuber M. Interdisciplinary tumour boards in Switzerland: quo vadis? Swiss Medical Weekly 2008; 138: 123-127
  • Laffer U, Metzger U, Aeberhard P, Lorenz M, Harder F, Maibach R, Zuber M, Herrmann R. Adjuvant perioperative portal vein or peripheral intravenous chemotherapy for potentially curative colorectal cancer: long-term results of a randomised controlled trial. Int J Colorectal Dis 2008; 23: 1223-1241
  • Straumann A, Bussmann C, Zuber M, Vannini S, Simon HU, Schoepfer A. Eosinophilic esophagitis: analysis of food impactation and perforation in 251 adolescent and adult patients. Clin Gastroenteol Hepatol 2008; 6: 598-600
  • Zuber M, Viehl CT, Güller U, Langer I. Aftercare recommendations for patients with curatively treated, invasive breast carcinoma. Ther Umschau 2008; 65: 319-321
  • Langer I, Guller U, Berclaz G, Koechli OR, Schaer G, Fehr MK, Hess T, Oertli D, Bronz L, Schnarwyler B, Wight E, Uehlinger U, Infanger E, Burger D, Zuber M, for the Swiss Multicentre Study Group Sentinel Lymph Node in Breast Cancer. Morbidity of sentinel lymph node biopsy (SLN) alone versus SLN & completion axillary lymph node dissection after breast cancer surgery: a prospective Swiss multicentre study on 659 patients Ann Surg 2007; 245: 452-461
  • Langer I, Guller U, Koechli OR, Berclaz G, Singer G, Schaer G, Fehr MK, Hess T, Oertli D, Bronz L, Schnrawyler B, Wight E, Uehlinger U, Infanger E, Burger D, Zuber M, for the Swiss Multicentre Sentinel Lymph Node Study Group in Breast Cancer. Association of the presence of bone marrow micrometastases with the sentinel lymph node status in 410 early stage breast cancer patients: Results of the Swiss multicenter study. Ann Surg Oncol 2007; 14: 1896-1903
  • Frey DM, Wildisen A, Hamel CT, Zuber M, Oertli D, Metzger J. Inguinal hernia repair: Lichtenstein versus mesh plug repair - a prospective randomised multicentre trial. Br J Surg 2007; 94: 63-4146. Viehl CT, Guller U, Hamel CT, Riehle HM, Plaass C, Marti WR, Oertli D, Zuber M. Carbon dye staining of sentinel lymph nodes facilitates microstaging of colon cancer patients. World J Surg 2006; 30: 453-456
  • Langer I, Marti WR, Guller U, Moch H, Harder F, Oertli D, Zuber M. Axillary recurrence rate in breast cancer patients with negative sentinel lymph node (SLN) or SLN micrometastases: prospective analysis of 150 patients after SLN biopsy. Ann Surg 2005; 241: 152-158
  • Köchli OR, Langer I, Berclaz G, Bischof T, Brun del Re R, Burkhard R, Delaloye JF, Diener PA, Haller U, Ries G, Schäfer P, Schär G, Steinert HC, von Orelli S, Zuber M. Sentinel lymph node biopsy in breast cancer. Consensus statements of the Swiss Working Group Sentinel in Breast Cancer and the Association of Gynaecological Oncology (AGO). Swiss Medical Journal 2005; 86: 48-56
  • Weber WP, Zanetti R, Langer I, Dellas S, Zuber M, Moch H, Remmel E, Oertli D, Wight E, Marti WR. Mammotome: Less invasive than ABBI with similar accuracy for early breast cancer detection. World J Surg 2005; 29: 495-499
  • Langer I, Kocher Th, Güller U, Torhorst J, Oertli D, Harder F, Zuber M. Long-term outcome of breast cancer patients after endoscopic axillary lymph node dissection: a prospective analysis of 52 patients. Breast Cancer Res Treat 2005; 90: 85-91
  • Al-Kuaya K, Schraml P, Torhorst J, Tapia C, Zaharieva B, Novotny H, Spichtin H, Maurer R, Mirlacher M, Köchli OR, Zuber M, Dietrich H, Mross F, Wilber K, Simon R, Sauter G. Prognostic relevance of gene amplifications and coamplifictions in breast cancer. Cancer Res 2004; 64: 8534-8540
  • Spizzo G, Went P, Dirnhofer S, Obrist P, Simon R, Spichtin H, Maurer R, Metzger U, Von Castelberg B, Bart R, Stopatschinskaya S, Köchli OR, Haas P, Mross F, Zuber M, Dietrich H, Bischoff S, Mirlacher M, Sauter G, Gastl G. High Ep-CAM expression is associated with poor prognosis in node negative breast cancer. Breast Cancer Res Treat 2004; 86: 207-213
  • Viehl CT, Hamel CT, Marti WR, Güller U, Eisner L, Stammberger U, Terracciano L, Spichtin HP, Harder F, Zuber M. Identification of sentinel lymph nodes in colon cancer depends on the amount of dye injected relative to tumour size. World J Surg 2003; 27: 1285-1290
  • Güller U, Nitzsche E, Moch H, Zuber M. Is positron emission tomography an accurate non-invasive alternative to sentinel lymph node biopsy in breast cancer patients? J Natl Cancer Inst 2003; 95: 1040-1043
  • Zuber M, Oertli D, Marti WR, Kocher T, Wildisen A, Berclaz G, Köchli OR, Harder F for the FMH Guideline Mammacarcinoma working group. FMH Guideline. Axillary surgery for breast carcinoma. Swiss Medical Journal 2003; 84: 1967-1973
  • Benz J, Berclaz G, Dupont Lampert V, Eicher E, Harder F, Köchli OR, Laffer UT, Poell JG, Trutmann M, Zuber M for the FMH Guideline Mammacarzinom, Chirurgische Therapie. FMH Guideline Tumorectomy or mastectomy? Choice of surgical procedure for stages T1-T3 NxM0 of breast carcinoma. Swiss Medical Journal 2003; 84: 1956-1965
  • Van de Rijn M, Perrou CM, Tibshirani R, Haas P, Kallioniemi O, Kononen J, Torhorst J, Sauter G, Zuber M, Kochli OR, Mross F, Dietrich H, Seitz R, Ross D, Botstein D, Brown P. Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome. Am J Path 2002; 161: 1991-1996
  • Güller U, Zajac P, Schnider A, Bösch B, Vorburger S, Zuber M, Spagnoli GC, Oertli D, Maurer R, Metzger U, Harder F, Heberer M, Marti WR. Disseminated single tumour cells as detected by real-time polymerase chain reaction represent a prognostic factor in patients undergoing surgery for colorectal cancer. Ann Surg 2002; 236: 768-776
  • Poremba C, Heine B, Diallo R, Heinecke A, Wai D, Schäfer KL, Braun Y, Schuck A, Lanvers C, Bankfalvi A, Kneif S, Torhorst J, Zuber M, Kochli OR, Mross F, Dietrich H, Sauter G, Stein H, Fogt F, Böcker W. Telomerase as a prognostic marker in breast cancer: high-throughput tissue microarray analysis of hTERT and hTR. J Path 2002; 198: 181-189
  • Güller U, Nitzsche EU, Schirp U, Viehl CT, Torhorst J, Moch H, Langer I, Marti WR, Oertli D, Harder F, Zuber M. Selective axillary surgery in breast cancer patients based on positron emission tomography with 18F-fluoro-2-deoxy-D-glucose: not yet. Breast Cancer Res Treat 2002; 71: 171-173
  • Güller U, Zuber M, Harder F. Zoecumvolvulus - a frequently missed diagnostic clinical picture. Results of a retrospective study of 26 patients and literature review. Swiss Surg 2001; 7: 158-164
  • Bittner C, Zuber M, Eisner L. Acute ischaemia of the hand in a drug addict after accidental intra-arterial injection. Swiss Surg 2002; 8: 281-284
  • Torhorst J, Bucher Ch, Kononen J, Haas Ph, Zuber M, Köchli OR, Mross F, Dieterich H, Moch H, Mihatsch M, Kallioniemi OP, Sauter G. Tissue microarrays for rapid linking of molecular changes to clinical endpoints. Am J Path 2001; 159: 2249-2256
  • Zuber M, Harder F. Breast carcinoma: Sentinel lymph node - guardian of intact regional lymph nodes. Practice 2001; 90: 835-838
  • Marti MR, Zuber M, Oertli D, Weber WP, Müller D, Köchli OR, Wasmer S, Metzger J, Langer I, Harder F. Advanced Breast Biopsy Instrumentation for the evaluation of nonpalpable lesions: a reliable tool with little therapeutic potential. Eur J Surg 2001; 167:15-18
  • Gambazzi F, Zuber M, Oertli D, Marti W, Kocher Th, Torhorst J, Harder F. Small breast carcinomas: less axillary surgery? Swiss Surg 2000; 6: 116-120
  • Langer I, Zuber M, Köchli OR, Kocher Th, Müller-Brand J, Torhorst J, Harder F. Validation study of the sentinel lymph node procedure in invasive breast carcinoma. Own data and review of the literature. Swiss Surg 2000; 6: 128-136
  • Kocher Th, Zuber M, Langer I, Harder F. Significance of endoscopic axillary dissection in invasive breast carcinoma after introduction of the sentinel lymph node procedure. Swiss Surg 2000; 6: 121-127
  • Marti WR, Zuber M, Oertli D, Weber WP, Müller D, Köchli OR, Wasmer S, Metzger J, Langer I, Harder F. The Advanced Breast Biopsy Instrumentation (ABBI) for the evaluation of mammographically suspicious, non-palpable findings of the mammary gland: a reliable diagnostic tool with low therapeutic potential. Swiss Surg 2000; 6: 111-115
  • Demartines N, Eisner L, Schnabel K, Fried R, Zuber M, Harder F. Evaluation of resonance cholangiography in the management of bile duct stones. Arch Surg 2000; 135: 148-152
  • Zuber M, Kocher Th, Langer I, Harder F. Value of endoscopic axillary dissection in invasive breast carcinoma. Acta Chir Austriaca 2000; 32: 1-5
  • Vorburger S, Zuber M, Renggli JC, Schnabel K. The window in the falciform ligament. A rare case of herniation of the small intestine through the falciform ligament. Chirurg 2000; 71: 466-468
  • Eppenberger U, Küng W, Schläppi JM, Rösel JL. Benz Ch, Müller H, Matter A, Zuber M, Lüscher K, Litschgi M, Schmitt M, Foekens JA, Eppenberger-Castori S. Markers of tumour angiogenesis and proteolysis (VEGF, uPA) independently define high- and low-risk subsets of node-negative breast cancer patients. J Clin Oncol 1998; 16: 3129-3136
  • Oertli D, Zuber M, Müller D, Marti WR, Köchli OR, Torhorst J, Harder F. First experiences with Advanced Breast Biopsy Instrumentation (ABBI), a system for stereotactic excision of non-palpable breast findings. Langenbecks Arch Surg, Surg Forum 1998; 383: 379-383
  • Kocher Th, Zuber M, Harder F. Endoscopic axillary dissection in invasive breast carcinoma. First experiences with a new technique. Zentralbl Chir 1998; 123: 98-99
  • Harder F, Zuber M, Kocher Th, Torhost J. Endoscopic surgery to the axilla - A replacement for conventional axillary clearance? Recent Results Cancer Res 1998; 152: 180-189
  • Metzger J, Krüss Ch, Kocher T, Ghisletta N, Zuber M, von Flüe M, Harder F. Mesh plug surgery: a simple, fast and low-complication technique for inguinal hernia repair. Schweiz Med Wochenschr 1998; 128: 1401-1407
  • Oertli D, Zuber M, Müller D, Marti WR, Köchli OR, Torhost J, Harder F. Advanced breast biopsy instrumentation (ABBI), a system for stereotactic excision of mammographically suspicious non-palpable findings of the mammary gland. Schweiz Med Wochenschr 1998; 6: 811-816
  • Harder F, Zuber M, Oertli D. Apparative diagnostics for treatment decisions - what is possible and desirable, what is dispensable and what is superfluous - in breast surgery. Langenbecks Arch Chir 1997; 382: 391-394
  • Zuber M, Spagnoli G, Lüscher U, Kocher T, Schaefer Ch, Noppen Ch, Gudat F, Harder F, Heberer M. Heterogeneity of melanoma antigen-1 (MAGE-1) gene and protein expression in malignant melanoma. Eur Surg Res 1997, 29: 403-410
  • Noppen Ch, Lüscher U, Zuber M, Spagnoli G, Schaefer Ch. Detection of tumour-associated antigen gene expression in peripheral blood by RT-PCR in combination with the mRNA isolation kit for blood/bone marrow. Biochemica 1997; 4: 11-13
  • Schaefer Ch, Noppen Ch, Nürnberger H, Gudat F, Kocher Th, Lüscher U, Zuber M, Spagnoli G, Heberer M. Immunohistochemical detection of MAGE tumour-associated antigens in esophageal squamous cell carcinoma. Oncol Rep 1997; 4: 1289-1293
  • Fischer C, Gudat F, Stulz P, Noppen Ch, Schaefer Ch, Zajac P, Trutmann M, Kocher Th, Zuber M, Harder F, Heberer M, Spagnoli G. Immunohistochemical analysis of MAGE-3 protein expression in non-small cell lung carcinomas. Int J Cancer 1997, 71: 1119-1121
  • Juretic A, Samija M, Spagnoli GC, Krajina Z, Zivkovic M, Herzeg T, Sobat H, Bistrovic M, Eljuga D, Turic m, Zuber M, Heberer M. Expression of cytokine genes in peripheral blood mononuclear cells of patients undergoing postmastectomy radiotherapy. Croatian Med J 1997; 38: 327-331
  • Juretic A, Jürgens-Göbel J, Schaefer Ch, Noppen C, Willimann T, Kocher Th, Zuber M, Harder F, Heberer M, Spagnoli G. Cytotoxic T-lymphocyte responses against mutated P21 ras peptides: an analysis of specific T-cell-receptor gene usage. Int J Cancer 1996, 68: 471-478
  • Gudat F, Zuber M, Dürrmüller U, Kocher Th, Schaefer Ch, Noppen Ch, Spagnoli G. The tumour-associated antigen MAGE-1 is detectable in formalin-fixed paraffin sections of malignant melanoma. Virchows Arch 1996, 429: 77-81
  • Zuber M, Heberer M, Lüscher U, Kocher Th, Harder F, Schaefer Ch, Gudat F, Spagnoli G. Heterogeneity of melanoma antigen-1 (MAGE-1) gene and protein expression in malignant melanoma. Surg Forum 1996, 47: 478-481
  • Kocher Th, Schraml P, Spagnoli G, Zuber M, Lüscher U, Harder F, Heberer M. Functional heterogeneity of melanoma cells of a single tumour biopsy. Langen¬becks Arch Chir, Chir Forum 1996; 381: 449-453
  • Zuber M, Heberer M, Luescher U, Kocher T, harder F, Schaefer C, Gudat F, Spagnoli GC. Heterogeneity of melanoma antigen-1 (MAGE-1) gene and protein expression in malignant melanoma. Surg Forum 1996; 478-481
  • Spagnoli G, Schaefer Ch, Willimann T, Kocher Th, Amoroso A, Juretic A, Zuber M, Lüscher U, Harder F, Heberer M. Peptide-specific CTL in tumour-infiltrating lymphocytes from metastatic melanomas expressing MART-1/Melan-A, gp 100 and tyrosinase genes: a study in an unselected group of HLA-A2.1-positive patients. Int J Cancer 1995, 64: 309-315
  • Kocher Th, Spagnoli G, Lüscher U, Zuber M, Juretic A, Schaefer Ch, Willimann T, Harder F, Heberer M. Tumour-infiltrating lymphocytes from metastatic melanoma recognise tumour antigen-derived peptides: A clinical study in a series of consecutive, unselected HLA-A2-positive patients. Surg Forum 1995, 46: 539-541
  • Dupont V, Zuber M, Laffer U, Harder F. Local treatment of breast carcinoma: When is breast-conserving therapy not suitable? Zentralbl Chir 1995, 120: 551-555
  • Schultz E, Juretic A, Dellabona P Lüscher U, Siegrist W, Harder F, Heberer M, Zuber M, Spagnoli G. MAGE-1 gene product is a cytoplasmic protein. Int J Cancer 1994, 59: 435-439
  • Zuber M, Lüscher U, Spagnoli G, Filgueira L, Juretic A, Kocher Th, Schultz E, Caetano V, Harder F, Heberer M. Cytokine gene expression in metastatic melanoma. Surg Forum 1994, 45: 519-521
  • Zuber M, Filgueira L, Merlo A, Lüscher U, Juretic A, Spagnoli G, Harder F, Heberer M. Interaction of tumour and immune system in renal cell carcinoma and melanoma. Cytokine gene transcription in tumours at the time of surgical resection. Swiss Medical Weekly 1994, 124: 930-935
  • Kocher Th, von Flüe M, Zuber M, Staub JJ, Scheidegger D, Harder F. Surgery for phaeochromocytoma. Development over 12 years. Schweiz Med Wo¬chenschr 1994, 124: 953-956
  • Lüscher U, Filgueira L, Juretic A, Zuber M, Heberer M, Spagnoli G. The pattern of cytokine gene expression in freshly excised human metastatic melanoma suggests a state of reversible anergy of tumour infiltrating lymphocytes. Int J Cancer 1994, 57: 612-619
  • Lüscher U, Zuber M, Filgueira L, Juretic A, Spagnoli G, Heberer M. Anergic lymphocytes from metastatic melanomas can be stimulated to tumour-specific cytotoxicity. Langenbecks Arch Chir, Chir Forum 1994; 379: 373-377
  • Goedegebuure PS, Zuber M, Leonard-Vidal DL, Burger UL, Cusack JC Jr, Chang MP, Douville LM, Eberlein TJ. Reactivation of murine tumour-infiltrating lymphocytes with solid-phase anti-CD3 antibody: in vitro cytokine production is associated with in vivo efficacy. Surg Oncol 1994, 3: 79-89
  • Filgueira L, Zuber M, Merlo A, Lüscher U, Schultz E, Caetano V, Harder F, Garotta G, Spagnoli G, Heberer M. Differential effects of IL-2 and CD3 triggering on cytokine gene transcription and secretion in tumour infiltrating lymphocytes. Cell Immunol. 1993, 150: 205-218
  • Spagnoli G, Juretic A, Schultz E, Dellabona P, Filgueira L, Hörig H, Zuber M, Garotta G, Heberer M. On the relative roles of Interleukin-2 and Interleukin-10 in the generation of lymphokine activated killer cell activity. Cell Immunol 1993, 146: 391-405
  • Filgueira L, Zuber M, Merlo A, Caetano V, Schultz E, Juretic A, Harder F, Spagnoli G, Heberer M. Cytokine transcription in renal cell carcinomas. Br J Surg 1993, 80: 1322-1325
  • Merlo A, Filgueira L, Zuber M, Harder F, Gratzl O, De Libero G, Heberer M, Spagnoli G. T-cell receptor V-gene usage in neoplasms of the central nervous system: a comparative analysis in cultured tumour infiltrating and peripheral blood T cells. J Neurosurg 1993, 78: 630-637
  • Filgueira L, Zuber M, Merlo A, Harder F, Heberer M, Spagnoli G. Effects of dif¬ferent cultureprotocols on the expression of discrete T-cell receptor variable regions in human tumour infiltrating lymphocytes. Eur J Cancer 1993, 29: 1754-1760
  • Merlo A, Juretic A, Zuber M, Filgueira L, Lüscher U, Caetano V, Ulrich J, Gratzl O, Heberer M, Spagnoli G. Cytokine gene expression in primary brain tumours, metastases and meningiomas suggests specific transcription pattern. Eur J Cancer 1992, 29: 2118-2125
  • Spagnoli GC, Zuber M, Merlo A, Gaetano V, Schultze E, Harder F, Filgueira L, Heberer M. Cytokine gene-transcription in renal cell carcinomas - a polymerase chain reaction study in tumour biopsies. J Cell Biochem 1993; 129
  • Zuber M, Filgueira L, Merlo A, Spagnoli G, Harder F, Heberer M. Activation of human tumour-infiltrating lymphocytes (TIL) with interleukin-2 and solid-phase anti-CD3 antibody. Langenbecks Arch Chir, Chir Forum 1992; 377: 239-245
  • Massaro AF, Schoof DD, Rubinstein A, Zuber M, Leonard-Vidal FJ, Eberlein TJ. Solid anti-CD3 anti¬body activation of murine tumour infiltrating lymphocytes. Cancer Res 1990, 50: 2587-2592
  • Eberlein TJ, Massaro AF, Rubinstein A, Leonard-Vidal FJ, Zuber M, Selleck C, Schoof DD. In vivo and in vitro effects of murine tumour infiltrating lymphocytes (TIL) restimulation by anti-CD3 antibody. Surg Forum 1989, 40: 428-430
  • Laffer U, Dürig M, Bloch HR, Zuber M, Stoll HR. Implantable catheter systems. Experiences in 205 patients. Dtsch med Wschr 1989, 114: 655-658
  • Rüedi Th, Balmer K, Zuber M. The fresh ligament ruptures of the upper ankle joint. Chirurg 1984, 55: 692-698
  • Important comments & correspondence
  • Dreyfuss JH. News & Views. Study finds omission of axillary lymph node dissection safe for patients with sentinel node micrometastases. CA A Cancer Journal for Clinicians 2010; 60: 2-3
  • Herrmann R, Lorenz M, Zuber M, Rufibach K, Laffer U. Perioperative and adjuvant chemotherapy in colon cancer: results of SAKK trial 40/93 Int J Colorectal Dis 2009; 24: 351-352
  • Fricker J. Sentinel node mapping for staging of colorectal cancer. The Lancet Oncology 2006; 7: 291
  • Zuber M. Invited commentary to: Yu JC et al. Prediction of metastases to non-sentinel nodes by sentinel node status and primary tumour characteristics in primary breast cancer in Taiwan. World J Surg 2005; 29: 813-819
  • Guller U, Oertli D, Zuber M. Correspondence to: Byrne AM et al. Positron emission tomography in the staging and management of breast cancer. Br J Surg 2004; 91: 1398-1409; www.bjs.co.uk/bjsCda/microViewCorrespondence.do
  • Original work (other)
  • Rueff J, Söllner O, Zuber M, Weixler B. Megaduodenum in a 59-year-old man: a very late postoperative complication after duodenal atresia. BMJ Case Rep 2018; doi: 10.1136/bcr-2017-221792
  • Zuber M, Langer I, Berclaz G, Köchli OR. Well-founded sentinel consensus thanks to data from the Swiss multicentre study. News letter SGS 2004; 4: 11-12
  • Güller U, Zuber M, Marti WR, Heberer M, Oertli D. Challenges in performing clinical trials in surgical oncology. swiss knife 2004; 1: 23-25
  • Zuber M. Axillary staging of breast cancer in Switzerland: Sentinel lymph node (SLN) biopsy: standard of care? News letter SGS 2003; 3: 4-6
  • Bittner C, Zuber M, Eisner L. Acute ischaemia of the hand in a drug addict after accidental intra-arterial injection. Swiss Surg 2002; 8: 281-284
  • Zuber M. Statement on sentinel lymphadenectomy. News letter SGS 2002; 2: 3-4
  • Zuber M, Harder F. Breast carcinoma: Sentinel lymph node - guardian of intact regional lymph nodes. Practice 2001; 90: 835-838
  • Viehl C, Nürnberger HR, Zuber M, Harder F. Pyoderma gangraenosum: Extensive defect formation in a mastectomy wound. Chir Practice 2001; 58: 63-68
  • Styger S, Demartines N, Zuber M, Harder F. Chronic gastric volvulus. Diagnosis and therapy. Chir Practice 2000; 57: 231-234
  • Kocher Th, Zuber M, Harder F. Minimally invasive surgery for breast carcinoma. Ther Umschau 1997; 54: 540-544
  • Rothenbühler JM, Ackermann C, Zuber M. The technique of bile duct revision. Helv chir Acta 1990, 57: 153-155
  • Zuber M, Bodoky A, Ackermann C. Emergency diagnosis of cecal volus. Helv chir Acta 1990, 57: 37-40
  • Zuber M. Antibiotic prophylaxis in colorectal surgery with kefazolin (Kefzol) - ornidazole (Tiberal) versus cefazolin - placebo. A prospective, randomised and controlled double-blind study. Dissertation, University of Basel, 1990
  • Vogelbach P, Harder F et al. A prospective follow-up study of 586 consecutive single-row extramucosal colonic anastomoses. Helv chir Acta 1988, 55: 655-658
  • Zuber M, Dürig M, Neff U, Laffer U. Antibiotic prophylaxis in colon surgery: chefazolin (Kefzol) - omidazole (Tiberal) versus cefazolin - placebo. Helv chir Acta 1989, 56: 211-215
  • Balmer K, Rüedi Th, Zuber M. The fibular ligament injury of the upper ankle joint. Contribution to X-ray diagnostics. Helv chir Acta 1985, 52: 201-204
  • Zuber M, Balmer K, Rüedi Th, Follow-up of surgically and conservatively treated lateral ligament ruptures of the upper ankle joint. Helv chir Acta 1984, 51: 633-640
  • Journal Publication
  • Zuber M, Vonlanthen R (eds). swiss knife 2004 - 2008
  • de Roche R, Ziegler S, Casanova G, Dutoit M, Zuber M. fmch direct. 2004 - 2007
  • Zuber M, Viehl CT (eds). Symposium Biel 2001 Advances in surgical oncology.Part II. Swiss Surg 2002; 8 (2)
  • Zuber M, Viehl CT (eds). Symposium Biel 2001: Advances in surgical oncology. Part I. Swiss Surg 2001; 7 (6)
  • Zuber M, Harder F (eds). 5th Postgraduate course in surgical oncology, Basel 1999. Early invasive breast cancer. Part II. Swiss Surg 2000; 6 (3)
  • Zuber M, Harder F (eds). ). 5th Postgraduate course in surgical oncology, Basel 1999. Early invasive breast cancer. Part I. Swiss Surg 1999; 5 (5)
  • Zuber M, von Flue M (eds). 4th Postgraduate course in surgical oncology, Basel 1997. colorectal cancer. Swiss Surg 1997; 3 (6)
  • Book chapter
  • Langer I, Guller U, Viehl CT, Zuber M. Sentinel lymph node metastases in breast cancer: prognostic relevance and therapeutic implications. Chapter in: From local invasion to metastatic cancer. Involvement of distant sites through the lymphovascular system. Leong SPL (ed). Humana Press / Springer. 2009: 339-345
  • Saha S, Sirop S, Soni M, Iddings D, Wiese D, Bilchik AJ, Beutler T, Ghanem M, Doan KA, Viehl CT, Zuber M. Sentinel lymph node mapping in colorectal cancer. Chapter in: From local invasion to metastatic cancer. Involvement of distant sites through the lymphovascular system. Leong SPL (ed). Humana Press / Springer. 2009: 361-379
  • Zuber M. Breast carcinoma. Chapter in Viehl CT, Oertli D (Ed). Specialist examination in surgery. A manual for exam preparation under the patronage of the Swiss Society of Surgery. 1st edition. EMH Scripts. 2009: 126-135
  • Oertli D, Zuber M. Spleen. Chapter in Siewert JR, Rothmund M, Schumpelick (Ed). Practice of Visceral Surgery. Gastroenterological surgery 2nd edition. Springer Verlag, Heidelberg 2006: 729-743
  • Saha S, Dan AG, Viehl CT, Zuber M, Wiese D. Sentinel lymph node mapping in colon and rectal cancer: its impact on staging, limitations, and pitfalls. Chapter in selective sentinel lymphadenectomy for human solid cancer. Leong SPL, Kitigawa Y, Kitajima M. (eds). Springer. Cancer Treat Res 2005; 127: 105-122
  • Zuber M, Harder F. Colonic volvulus. Chapter in Siewert JR, Harder F, Rothmund M (Ed). Practice of Visceral Surgery. Gastroenterological Surgery Volume I. Springer Verlag, Heidelberg 2002; I: 518-531
  • Oertli D, Zuber M, Harder F. Spleen. Chapter in Siewert JR, Harder F, Rothmund M (Ed). Practice of Visceral Surgery. Gastroenterological Surgery Volume I. Springer Verlag, Heidelberg 2002; I: 855-872
  • Zuber M, Harder F. Benign tumours of the colon and rectum. Evidence-based and problem-oriented. Holzheimer RG, Mannick JA (eds). W Zuckerschwerdt Publishers Munich, New York. 2001: 172-178
  • Zuber M, Kocher T, Oertli D, Gambazzi F, Müller D, Köchli O, Torhost J, Harder F. The "sentinel lymph node" procedure as a selection criterion for axillary lymph node dissection in breast carcinoma. In: Laffer U, Oertli D, Dürig M, Harder F (Ed): Ethics, technique and concepts: 10 years later. Basler Beitr Chir, Schwabe, Basel 1998; 10: 209-216
  • Kocher Th, Zuber M, Oertli D, Harder F. Endoscopic axillary dissection in invasive breast carcinoma - First experiences with a new technique. In: Laffer U, Oertli D, Dürig M, Harder F (Ed): Ethics, technique and concepts: 10 years later. Basler Beitr Chir, Schwabe, Basel 1998: 10: 217-221
  • Oertli D, Zuber M, Müller D, Marti W.R. Köchli O.R. Torhost J, Harder F. First experiences with Advanced Breast Biopsy Instrumentation (ABBI), a system for stereotactic excision of non-palpable breast findings. In: Laffer U, Oertli D, Dürig M, Harder F (Ed): Ethics, technique and concepts: 10 years later. Basler Beitr Chir, Schwabe, Basel 1998; 201-207
  • Zuber M. Liver cancer. Series: Patient information (leaflets) of the Swiss Cancer League, Bern 1997
  • Revision for the 15th International Practical Course in Gastroenterological Surgery, Davos 1998
  • Revised version for the 14th International Practical Course in Gastroenterological Surgery, Davos 1997
  • Zuber M, Bertschi V (eds). Manuscript for practical exercises. Workshop in gastrointestinal surgery. International Gastrointestinal Surgery Workshop, Davos 1996
  • Revision for the 15th International Practical Course in Gastroenterological Surgery, Davos 1998
  • Revised version for the 14th International Practical Course in Gastroenterological Surgery, Davos 1997
  • Zuber M, Bertschi V (Ed). Manuscript for practical exercises. 13th International Practical Course in Gastroenterological Surgery, Davos 1996
  • Juretic A, Spagnoli G, Heberer M, Zuber M, Harder F, Samija M, Eljuga D, Turic M. Induction of a cytotoxic T lymphocyte response in vitro against peptides encompassing mutations in the ras oncogene. In: Osmak M, Skrk J (eds). Molecular oncology today. Proceedings of the Croatian-Slovenian Meeting, Zagreb 1996: 15-19
  • Zuber M. Gallbladder cancer. Series: Patient information (leaflets) from the Swiss Cancer League, Bern 1995
  • Metzger U, Zuber M. Malignancies of the small bowel. In: Peckham M, Pinedo B, Veronesi U (Ed). Oxfort Textbook of Oncology. Oxford University Press, Oxford (GB) 1995: 1130-1133
  • Merlo A, Filgueira L, Zuber M, Lüscher U, Caetano V, Schultz E, Juretic A, Gratzl O, Spagnoli G, Heberer M. Detection of the inhibitory cytokines TGF- 2 and interleukin-10 in primary neoplasia: cause of functional inactivation of tumour-infiltrating lymphocytes? In: Laffer U, de Roche R, Harder F (eds). Models of interdisciplinary action. Basler Beitr Chir, Karger, Basel 1993; 5: 76-80
  • Zuber M, Filgueira L, Merlo A, Lüscher U, Caetano V, Schultz E, Juretic A, Harder F, Spagnoli G, Heberer M. Cytokine transcription in renal cell carcinomas. In: Laffer U, de Roche R, Harder F (Ed). Models of interdisciplinary action. Basler Beitr Chir, Karger, Basel 1993; 5: 81-85
  • Filgueira L, Spagnoli G, Zuber M, Merlo A, Gasser T, Bucheli B, Heberer M, Harder F. Differential TCR-V gene usage in isolated human tumour infiltrating and autologous peripheral lymphocytes. In: Malavasi F, Cortese R, Albertini A (eds). European Biotechnology Today: The impact of basis science on diagnosis and therapy. Intercept Ltd, Andover (GB) 1992: 129-135
  • Zuber M, Laffer U, Harder F. Preventive Surgery. In: Weber W (ed). Familial cancer control. Monographs (Veronesi U, series ed) European School of Onco¬logy. Springer, Berlin, Heidel-berg, New York 1992: 59-64
  • Harder F, Vogelbach P, Zuber M. The continuous single-row intestinal anastomosis. In: Lamesch A (ed). Modern concepts and new techniques in paediatric surgery. Bulletin de la Societé des Sciences medicales du Grand-Duche de Luxembourg, Chirurgie pédiatrique 1989; 126 III: 55-60
  • Zuber M, Frede KF. The cecal volus. In: Laffer U, Dürig M (Ed): Ethics, Technique and Concepts, Basler Beitr Chir. Karger, Basel 1989; 1: 125-131